‘The next is nanopores, and that is our oldest line of research and that has now triggered DNA sequencers dependant on nanopores. We pull individual DNA strands via a nanopore and will then examine from the nucleotide sequence. Pretty recently, we even managed to read out only one protein for The 1st time employing This method. But this line of study is not just about developing applications, but will also about authentic biological concerns.

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Dynamics of initiation, termination and reinitiation of DNA translocation with the motor protein EcoR124I

Deposition and atomic power microscopy of personal phthalocyanine polymers among nanofabricated electrodes

2010, produced a whole new way (‘wedging transfer’) to govern nanostructures; to start with report of DNA translocation through graphene nanopores; and understood hybrid nanopores by directed insertion of α-hemolysin into good-state nanopores

Our analysis ranges through the biophysics of DNA to synthetic cells and beyond. Please take a look below at the spectrum of our current projects.

Numerous connected developments followed, in which our group set up distinct transistor variants for example solitary-electron transistors at area temperature and intramolecular nanotube junctions that acted as rectifying diodes, and coupled various transistors into compact evidence-of-basic principle electronic circuits.

Learning DNA loop extrusion by SMC proteins for chromosome architecture with one-molecule assays.

The rotors harness Vitality from the nanoscale drinking water and ion movement that's created by a static chemical or electrochemical likely gradient inside the nanopore, that happen to be set up via a salt gradient or utilized voltage, respectively. These artificial nanoengines self-Arrange and operate autonomously in physiological disorders, suggesting strategies to constructing Electricity-transducing motors at nanoscale interfaces.

Bulk-surface area coupling identifies the mechanistic link amongst Min-protein styles in vivo As well as in vitro

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Instance (two) of bending configurations in 3D simulations of DNA rods on nanopores. A part of the membrane is revealed in grey, the rim of your pore is highlighted in crimson, and a 3D rendering on the motion on the DNA rod is exhibited.